What it does
Selenium works with vitamin E to prevent nutritional muscular dystrophy, equine degenerative myeloencephalopathy and equine motor neuron disease [1].
Deficiency
Deficiency lowers serum selenium and raises AST, and causes white muscle disease and perhaps tying-up (rhabdomyolysis) in working horses [1]. Acidic soils in some regions are deficient, and horses there may need supplementation [1].
Toxicity
Selenium has a very narrow range of safety [1]. Forage grown on alkaline soils in some regions can contain enough selenium to be toxic [1].
Signs of acute toxicity include apparent blindness, head pressing, sweating, faster heart and breathing rates, and lethargy. Chronic toxicity causes loss of mane and tail hair and cracking of the hoof at the coronary band [1].
Idle mature horses gain no advantage from extra selenium above their requirement [1].
Interactions
Excess copper may reduce selenium absorption [1].
Sources
- 1. Liburt NR (peer reviewed by Boyle AG). Nutritional Requirements of Horses and Other Equids. MSD Veterinary Manual, Professional Version. Merck & Co., Inc., Rahway, NJ. Last full review February 2026. https://www.msdvetmanual.com/management-and-nutrition/nutrition-horses/nutritional-requirements-of-horses (accessed 2026-11-07)
Last edited 7 Nov 2026, 1:48 am